This renovated passenger train depot, located on Blues Alley, has been lovingly refurbished to its original condition both inside and out. Together, Clarksdale Station, the Delta Blues Museum, the former Greyhound Bus Station, and Ground Zero Blues Club make up Blues Alley.
Clarksdale Station houses several businesses including the Depot restaurant and the Dutch Oven restaurant and bakery, and also has a performance hall and other spaces for lease to private entrepreneurs seeking space in the Blues Alley area.